en ميکروب شناسي Microbiology گزارش مورد Case Report Infective endocarditis is rare in children but can cause significant morbidity and mortality. <em>Streptococcus</em> and <em>Staphylococcus</em> species are the leading causes of this disease. <em>Staphylococcus</em> is more common in people with underlying heart disease, and <em>Streptococcus viridans</em> is more common in people who have had a dental procedure. In general, any fever of unknown origin in children with an underlying heart problem should be carefully evaluated for endocarditis, and empiric therapy should be performed. The main symptoms of the disease include fever, new murmur, deterioration of the previous murmur, hematuria, embolic events, splenomegaly, bleeding splinter, Osler&#39;s nodes, Janeway lesion, and Roth spots. One of the important complications of infective endocarditis is cerebrovascular event and stroke. Herein, we describe a 6-year-old girl presented with fever and skin lesions and no history of underlying heart problem or dental procedure. The patient expired after three days of mitral valve infection with <em>S. aureus</em>. Staphylococcus aureus,endocarditis,Stroke, 58 62 http://mlj.goums.ac.ir/browse.php?a_code=A-10-1033-1&slc_lang=en&sid=1 Mohsen Ebrahimi m1355ebrahimi@gmail.com 100319475328460022381 100319475328460022381 No Children's Research Center, Golestan University of Medical Sciences, Gorgan, Iran Hassan Esmaeili he_md1972@yahoo.com 100319475328460022382 100319475328460022382 Yes Children's Research Center, Golestan University of Medical Sciences, Gorgan, Iran